{"id":367,"date":"2016-11-17T09:41:49","date_gmt":"2016-11-17T08:41:49","guid":{"rendered":"https:\/\/www.biogalenys.com\/test-dirritation-occulaire"},"modified":"2020-01-28T12:56:12","modified_gmt":"2020-01-28T11:56:12","slug":"ocular-irritation-test","status":"publish","type":"page","link":"https:\/\/www.biogalenys.com\/en\/in-vitro-toxicology\/ocular-irritation-test","title":{"rendered":"Ocular irritation test"},"content":{"rendered":"<div id=\"themify_builder_content-367\" data-postid=\"367\" class=\"themify_builder_content themify_builder_content-367 themify_builder\">\n    \t<!-- module_row -->\n\t<div  class=\"themify_builder_row module_row clearfix module_row_0 themify_builder_367_row module_row_367-0 tb_hv28808\">\n\t    \t    <div class=\"row_inner col_align_top\" >\n\t\t\t<div  class=\"module_column tb-column col-full   first tb_367_column module_column_0 module_column_367-0-0 tb_mjb2100\">\n\t    \t    \t        <div class=\"tb-column-inner\">\n\t\t    <!-- module text -->\n<div  class=\"module module-text tb_xndw380    \">\n            <div  class=\"tb_text_wrap\">\n    <h1>IN VITRO TOXICOLOGY \u2013 OCULAR IRRITATION TEST<\/h1>    <\/div>\n<\/div>\n<!-- \/module text -->\n<!-- module text -->\n<div  class=\"module module-text tb_qquq300    \">\n            <div  class=\"tb_text_wrap\">\n    <p>The laboratory offers ocular irritation tests.<\/p><h3>Neutral red uptake assay:<\/h3><p>This is an alternative to animal testing, part of a series of tests for assessing the ocular irritant potential of cosmetic products.<\/p><p>The principle is based on evaluating the cytotoxicity of the tested product by determining the concentration that leads to 50% mortality of the corneal fibroblasts (CI50) by using a technique involving the uptake of neutral red.<\/p><h3>MTT conversion assay<\/h3><p>This ocular tolerance test is carried out on human corneal epithelium reconstructed from 0.5cm\u00b2 obtained from transformed human corneal keratinocytes (SkinEthic\u2122).<\/p><p>The ocular irritant potential of the product being tested is determined by testing cellular viability (MTT).<\/p>    <\/div>\n<\/div>\n<!-- \/module text -->\n\t        <\/div>\n\t    \t<\/div>\n\t\t    <\/div>\n\t    <!-- \/row_inner -->\n\t<\/div>\n\t<!-- \/module_row -->\n\t\t<!-- module_row -->\n\t<div   class=\"themify_builder_row module_row clearfix fullwidth_row_container module_row_1 themify_builder_367_row module_row_367-1 tb_4xg1378\">\n\t    \t    <div class=\"row_inner col_align_top\" >\n\t\t\t<div  class=\"module_column tb-column col-full   first tb_367_column module_column_0 module_column_367-1-0 tb_rupp807\">\n\t    \t    \t        <div class=\"tb-column-inner\">\n\t\t    \t<div  class=\"themify_builder_sub_row module_subrow clearfix sub_row_1-0-0 tb_dohu003\">\n\t    \t    <div class=\"subrow_inner col_align_top\" >\n\t\t\t<div  class=\"sub_column module_column col4-2  first sub_column_post_367 sub_column_1-0-0-0 tb_w8uo000\"> \n\t    \t    \t        <div class=\"tb-column-inner\">\n\t\t    <!-- module text -->\n<div  class=\"module module-text tb_xga1570    \">\n            <div  class=\"tb_text_wrap\">\n    <h2>Application<\/h2><ul><li>Cosmetic products<\/li><li>Cosmetic ingredients<\/li><\/ul>    <\/div>\n<\/div>\n<!-- \/module text -->\n\t        <\/div>\n\t    \t<\/div>\n\t\t<div  class=\"sub_column module_column col4-2  last sub_column_post_367 sub_column_1-0-0-1 tb_qumc503\"> \n\t    \t    \t        <div class=\"tb-column-inner\">\n\t\t        <!-- module image -->\n    <div  class=\"module module-image tb_hiqo080   image-top  \">\n\t                <div class=\"image-wrap\">\n                            <a href=\"https:\/\/www.biogalenys.com\/wp-content\/uploads\/2017\/03\/IrritaOculaire1.jpg\"\n                   class=\"lightbox-builder themify_lightbox\"                   >\n                                               <span class=\"zoom ti-search\"><\/span>\n                                        <img loading=\"lazy\" decoding=\"async\" width=\"450\" height=\"396\" src=\"https:\/\/www.biogalenys.com\/wp-content\/uploads\/2017\/03\/IrritaOculaire1.jpg\" class=\" wp-post-image wp-image-1433\" alt=\"IrritaOculaire1\" srcset=\"https:\/\/www.biogalenys.com\/wp-content\/uploads\/2017\/03\/IrritaOculaire1.jpg 450w, https:\/\/www.biogalenys.com\/wp-content\/uploads\/2017\/03\/IrritaOculaire1-300x264.jpg 300w\" sizes=\"auto, (max-width: 450px) 100vw, 450px\" \/>                <\/a>\n            \n                        <\/div>\n            <!-- \/image-wrap -->\n        \n        \n        <\/div>\n    <!-- \/module image -->\n\t        <\/div>\n\t    \t<\/div>\n\t\t    <\/div>\n\t<\/div><!-- \/themify_builder_sub_row -->\n\t\t        <\/div>\n\t    \t<\/div>\n\t\t    <\/div>\n\t    <!-- \/row_inner -->\n\t<\/div>\n\t<!-- \/module_row -->\n\t<\/div>\n\n\n","protected":false},"excerpt":{"rendered":"<p>IN VITRO TOXICOLOGY \u2013 OCULAR IRRITATION TEST The laboratory offers ocular irritation tests. Neutral red uptake assay: This is an alternative to animal testing, part of a series of tests for assessing the ocular irritant potential of cosmetic products. The principle is based on evaluating the cytotoxicity of the tested product by determining the concentration [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":405,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"inline_featured_image":false,"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-367","page","type-page","status-publish","hentry","has-post-title","has-post-date","has-post-category","has-post-tag","has-post-comment","has-post-author",""],"_links":{"self":[{"href":"https:\/\/www.biogalenys.com\/en\/wp-json\/wp\/v2\/pages\/367","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.biogalenys.com\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.biogalenys.com\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.biogalenys.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.biogalenys.com\/en\/wp-json\/wp\/v2\/comments?post=367"}],"version-history":[{"count":0,"href":"https:\/\/www.biogalenys.com\/en\/wp-json\/wp\/v2\/pages\/367\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/www.biogalenys.com\/en\/wp-json\/wp\/v2\/pages\/405"}],"wp:attachment":[{"href":"https:\/\/www.biogalenys.com\/en\/wp-json\/wp\/v2\/media?parent=367"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}