{"id":388,"date":"2016-11-17T09:24:04","date_gmt":"2016-11-17T08:24:04","guid":{"rendered":"https:\/\/www.biogalenys.com\/passage-transmembranaire\/trans-muqueux"},"modified":"2020-01-29T07:25:43","modified_gmt":"2020-01-29T06:25:43","slug":"transmucosal-permeation","status":"publish","type":"page","link":"https:\/\/www.biogalenys.com\/en\/transmembrane-permeation\/transmucosal-permeation","title":{"rendered":"Transmucosal permeation"},"content":{"rendered":"<div id=\"themify_builder_content-388\" data-postid=\"388\" class=\"themify_builder_content themify_builder_content-388 themify_builder\">\n    \t<!-- module_row -->\n\t<div  class=\"themify_builder_row module_row clearfix module_row_0 themify_builder_388_row module_row_388-0 tb_gtfr500\">\n\t    \t    <div class=\"row_inner col_align_top\" >\n\t\t\t<div  class=\"module_column tb-column col-full   first tb_388_column module_column_0 module_column_388-0-0 tb_f16r810\">\n\t    \t    \t        <div class=\"tb-column-inner\">\n\t\t    <!-- module text -->\n<div  class=\"module module-text tb_485k914    \">\n            <div  class=\"tb_text_wrap\">\n    <h1>TRANSMUCOSAL<\/h1><p>\u00a0<\/p>    <\/div>\n<\/div>\n<!-- \/module text -->\n<!-- module text -->\n<div  class=\"module module-text tb_ztj9303    \">\n            <div  class=\"tb_text_wrap\">\n    <p>Transmucosal permeation is often favoured when it is necessary to circumvent the first pass hepatic effect.\u00a0<\/p><p>Transmucosal permeation studies make it possible to test the speedy absorption of active ingredients, indispensable for this delivery method.<\/p><p><strong>Biogalenys carries out nasal and oral absorption studies <\/strong>with equipment that is adapted to membrane physiology and its natural functioning.<\/p><p>These studies are carried out either using Ussing chambers or in Franz cell membranes, and make it possible to:<\/p><ul><li>Test the permeability and capacity of mucosal membranes to create rapid absorption using the different methods.<\/li><li>Determine the influence of excipients and their composition on permeation.<\/li><li>Develop galenic preparations (gels, solutions, emulsions, sprays).<\/li><\/ul>    <\/div>\n<\/div>\n<!-- \/module text -->\n<!-- module text -->\n<div  class=\"module module-text tb_o2gz160    \">\n            <div  class=\"tb_text_wrap\">\n    <h2>Oral, nasal, vaginal, sublingual delivery<\/h2>    <\/div>\n<\/div>\n<!-- \/module text -->\n    <!-- module image -->\n    <div  class=\"module module-image tb_t7m8040   image-top  \">\n\t                <div class=\"image-wrap\">\n                            <a href=\"https:\/\/www.biogalenys.com\/wp-content\/uploads\/2017\/04\/Mucus.jpg\"\n                   class=\"lightbox-builder themify_lightbox\"                   >\n                                               <span class=\"zoom ti-search\"><\/span>\n                                        <img loading=\"lazy\" decoding=\"async\" width=\"950\" height=\"463\" src=\"https:\/\/www.biogalenys.com\/wp-content\/uploads\/2017\/04\/Mucus.jpg\" class=\" wp-post-image wp-image-1672\" alt=\"Mucus\" srcset=\"https:\/\/www.biogalenys.com\/wp-content\/uploads\/2017\/04\/Mucus.jpg 950w, https:\/\/www.biogalenys.com\/wp-content\/uploads\/2017\/04\/Mucus-300x146.jpg 300w, https:\/\/www.biogalenys.com\/wp-content\/uploads\/2017\/04\/Mucus-768x374.jpg 768w\" sizes=\"auto, (max-width: 950px) 100vw, 950px\" \/>                <\/a>\n            \n                        <\/div>\n            <!-- \/image-wrap -->\n        \n        \n        <\/div>\n    <!-- \/module image -->\n\t        <\/div>\n\t    \t<\/div>\n\t\t    <\/div>\n\t    <!-- \/row_inner -->\n\t<\/div>\n\t<!-- \/module_row -->\n\t<\/div>\n\n\n","protected":false},"excerpt":{"rendered":"<p>TRANSMUCOSAL \u00a0 Transmucosal permeation is often favoured when it is necessary to circumvent the first pass hepatic effect.\u00a0 Transmucosal permeation studies make it possible to test the speedy absorption of active ingredients, indispensable for this delivery method. Biogalenys carries out nasal and oral absorption studies with equipment that is adapted to membrane physiology and its [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":387,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"inline_featured_image":false,"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-388","page","type-page","status-publish","hentry","has-post-title","has-post-date","has-post-category","has-post-tag","has-post-comment","has-post-author",""],"_links":{"self":[{"href":"https:\/\/www.biogalenys.com\/en\/wp-json\/wp\/v2\/pages\/388","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.biogalenys.com\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.biogalenys.com\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.biogalenys.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.biogalenys.com\/en\/wp-json\/wp\/v2\/comments?post=388"}],"version-history":[{"count":0,"href":"https:\/\/www.biogalenys.com\/en\/wp-json\/wp\/v2\/pages\/388\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/www.biogalenys.com\/en\/wp-json\/wp\/v2\/pages\/387"}],"wp:attachment":[{"href":"https:\/\/www.biogalenys.com\/en\/wp-json\/wp\/v2\/media?parent=388"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}