TRANSOCULAR

  • Studies of transscleral/transcorneal permeation with modified Franz diffusion cell assembly or Ussing chamber (Biogalenys).
  • Reverse transport study, impact of P-glycoprotein (cornea).
  • Pharmacokinetic studies and distribution of topical preparations (cornea, lens, aqueous humour, retina, sclera).
  • Stability and enzymatic hydrolysis studies (determining Vi Km and Vmax).
  • Pharmokinetic studies following intra-vitreous administration or deposit (vitreous humour, choroid, retina).

 

Application

  • Solutions
  • Eye drops
  • Gels
  • Topical medication
  • Intra-vitreous implants and deposits

BIOGALENYS transcorneal flux indicators